Presentación    
DIAGNOSIS AND TREATMENT OF DISEASES ASSOCIATED WITH ABNORMALITIES OF THE COMPLEMENT SYSTEM
Publications
Publications 2014
DOCUMENT I.F. CUARTILE
Charignon, D.; Ghannam, A.; Defendi, F.; Ponard, D.; Monnier, N.; Trascasa, M. L.; Launay, D.; Caballero, T.; Djenouhat, K.; Fain, O.; Cichon, S.; Martin, L.; Drouet, C. Hereditary angioedema with F12 mutation: factors modifying the clinical phenotype. ALLERGY. 2014; 69(12): 1659-1665. Artículo. 6,028 D1
Blom, A. M.; Volokhina, E. B.; Fransson, V.; Stromberg, P.; Berghard, L.; Viktorelius, M.; Mollnes, T. E.; López-Trascasa, M.; van den Heuvel, L. P.; Goodship, T. H.; Marchbank, K. J.; Okroj, M. A novel method for direct measurement of complement convertases activity in human serum. CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2014; 178(1): 142-153. Artículo. 3,037 Q2
Chinchilla, D. S.; Pinto, S.; Hoppe, B.; Adragna, M.; López, L.; Roldán, M. L. J.; Peña, A.; Trascasa, M. L.; Sánchez-Corral, P.; de Córdoba, S.R. Complement mutations in diacylglycerol kinase-epsilon-associated atypical hemolytic uremic syndrome. CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 2014; 9(9): 1611-1619. Artículo. 4,613 Q1
Tenorio, J.; Mansilla, A.; Valencia, M.; Martínez-Glez, V.; Romanelli, V.; Arias, P.; Castrejón, N.; Poletta, F.; Guillén-Navarro, E.; Gordo, G.; Mansilla, E.; García-Santiago, F.; González-Casado, I.; Vallespín, E.; Palomares, M.; Mori, MA.; Santos-Simarro, F.; García-Miñaur, S.; Fernández, L.; Mena, R.; Benito-Sanz, S.; del Pozo, A.; Silla, J. C.; Ibáñez, K.; López-Granados, E.; Martín-Trujillo, A.; Montaner, D.; Heath, K. E.; Campos-Barros, A.; Dopazo, J.; Nevado, J.; Monk, D.; Ruiz-Pérez, V. L.; Lapunzina, P. A new overgrowth syndrome is due to mutations in RNF125. HUMAN MUTATION. 2014; 35(12): 1436-1441. Artículo. 5,144 Q1
Jozsi, M.; Reuter, S.; Nozal, P.; López-Trascasa, M.; Sánchez-Corral, P.; Prohaszka, Z.; Uzonyi, B. Autoantibodies to complement components in C3 glomerulopathy and atypical hemolytic uremic syndrome. IMMUNOLOGY LETTERS. 2014; 160(2): 163-171. Artículo. 2,512 Q1
Nozal, P.; Garrido, S.; Alba-Domínguez, M.; Espinosa, L.; Peña, A.; de Córdoba, S. R.; Sánchez-Corral, P.; López-Trascasa, M. An ELISA assay with two monoclonal antibodies allows the estimation of free factor H and identifies patients with acquired deficiency of this complement regulator. MOLECULAR IMMUNOLOGY. 2014; 58: 194-200. Artículo. 2,973 Q2
López-Lera, A.; Pernía, O.; López-Trascasa, M.; Cáceres, I. I. Expression of the SERPING1 gene is not regulated by promoter hypermethylation in peripheral blood mononuclear cells from patients with hereditary angioedema due to C1-inhibitor deficiency. ORPHANET JOURNAL OF RARE DISEASES. 2014; 9: 103. Artículo. 3,358 Q2
Sánchez-Moreno, A.; de la Cerda, F.; Cabrera, R.; Fijo, J.; López-Trascasa, M.; Bedoya, R.; de Córdoba, S. R.; Ybot-González, P. Eculizumab in dense-deposit disease after renal transplantation. PEDIATRIC NEPHROLOGY. 2014; 29(10): 2055-2059. Artículo. 2,856 Q1
Román-Ortiz, E.; Oteiza, S. M.; Pinto, S.; López-Trascasa, M.; Sánchez-Corral, P.; de Córdoba, S. R. Eculizumab long-term therapy for pediatric renal transplant in aHUS with CFH/CFHR1 hybrid gene. PEDIATRIC NEPHROLOGY. 2014; 29(1): 149-153. Artículo. 2.856 Q1
López-Lera, A.; Torres-Canizales, J. M.; Garrido, S.; Morales, A.; López-Trascasa, M. Rothmund-Thomson syndrome and glomerulonephritis in a homozygous C1q-deficient patient due to a Gly164Ser C1qC Mutation. JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2014; 134(4): 1152-1154. Carta. 7,219 D1
Nevado, J.; Mergener, R.; Palomares-Bralo, M.; Souza, K. R.; Vallespín, E.; Mena, R.; Martínez-Glez, V.; Mori, M. A.; Santos, F.; García-Miñaur, S.; García-Santiago, F.; Mansilla, E.; Fernández, L.; de Torres, M. L.; Riegel, M.; Lapunzina, P. New microdeletion and microduplication syndromes: a comprehensive review. GENETICS AND MOLECULAR BIOLOGY. 2014; 37(1): 210-219. Revisión. 1,202 Q4
Publications 2009 - 2013
YEAR NAME I.F. CUARTILE
2013 Tortajada, A.; Yébenes, H.; Abarrategui-Garrido, C.; Anter, J.; García-Fernández, J. M.; Martínez-Barricarte, R.; Alba-Domínguez, M.; Malik, T. H.; Bedoya, R.; Pérez, R. C.; Trascasa, M. L.; Pickering, M. C.; Harris, C. L.; Sánchez-Corral, P.; Llorca, O.; de Córdoba, S. R. C3 glomerulopathy-associated CFHR1 mutation alters FHR oligomerization and complement regulation. JOURNAL OF CLINICAL INVESTIGATION. 2013; 123(6): 2434-2446. Artículo. 13,765 D1
2013 Hebecker, M.; Alba-Domínguez, M.; Roumenina, L. T.; Reuter, S.; Hyvarinen, S.; Dragón-Durey, M. A.; Jokiranta, T. S.; Sánchez-Corral, P.; Jozsi, M. An Engineered construct combining complement regulatory and surface-recognition domains represents a minimal-size functional factor H. JOURNAL OF IMMUNOLOGY. 2013; 191(2): 912-921. Artículo. 5,362 D1
2013 Bresin, E.; Rurali, E.; Caprioli, J.; Sánchez-Corral, P.; Fremeaux-Bacchi, V.; de Córdoba, S. R.; Pinto, S.; Goodship, T. H. J.; Alberti, M.; Ribes, D.; Valoti, E.; Remuzzi, G.; Noris, M. Combined complement gene mutations in atypical hemolytic uremic syndrome influence clinical phenotype. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 2013; 24(3): 475-486. Artículo. 9,466 D1
2013 López-Lera, A.; Cabo, F. S.; Garrido, S.; Dopazo, A.; López-Trascasa, M. Disease-modifying factors in hereditary angioedema: an RNA expression-based screening. ORPHANET JOURNAL OF RARE DISEASES. 2013; 8: 77. Artículo. 3,958 Q1
2013 Gómez-Traseira, C; López-Lera, A; Drouet, C; López-Trascasa,
M; Pérez-Fernández, E; Favier, B; Prior, N; Caballero, T. Hereditary
angioedema caused by the p.Thr309-Lys mutation in the F12 gene: A multifactorial disease. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2013; 132(4): 986-989. Carta.
11,248 D1
2012 Ariceta, G.; Arrizabalaga, B.; Aguirre, M.; Morteruel, E.; López-Trascasa, M. Eculizumab in the treatment of atypical hemolytic uremic syndrome in infants. AMERICAN JOURNAL OF KIDNEY DISEASES. 2012; 59(5): 707-710. Article. 5,294 D1
2012 Leban, N.; Abarrategui-Garrido, C.; Fariza-Requejo, E.; Amiñoso-Carbonero, C.; Pinto, S.; Chibani, J. B.; Khelil, A. H.; Sánchez-Corral, P. Factor H and CFHR1 polymorphisms associated with atypical haemolytic uraemic syndrome (aHUS) are differently expressed in tunisian and in caucasian populations. INTERNATIONAL JOURNAL OF IMMUNOGENETICS. 2012; 39(2): 110-113. Article.   1,355 Q4
2012 Kopp, A.; Strobel, S.; Tortajada, A.; de Córdoba, S. R.; Sánchez-Corral, P.; Prohaszka, Z.; López-Trascasa, M.; Jozsi, M. Atypical hemolytic uremic syndrome-associated variants and autoantibodies impair binding of factor H and factor HRelated Protein 1 to Pentraxin 3. JOURNAL OF IMMUNOLOGY. 2012; 189(4): 1858-1867. Article.  5,52 Q1
2012 Paixao-Cavalcante, D.; López-Trascasa, M.; Skattum, L.; Giclas,
P. C.; Goodship, T. H.; de Córdoba, S. R.; Truedsson, L.; Morgan, B. P.; Harris, C. L. Sensitive and specifi c assays for C3 nephritic factors clarify mechanisms underlying complement dysregulation. KIDNEY INTERNATIONAL. 2012; 82(10): 1084-1092. Article.
7,916 D1
2012 Tortajada, A.; Pinto, S.; Martínez-Ara, J.; López-Trascasa, M.; Sánchez-Corral, P.; de Córdoba, S. R. Complement factor H variants I890 and L1007 while commonly associated with atypical hemolytic uremic syndrome are polymorphisms with no functional signifi cance. KIDNEY INTERNATIONAL. 2012; 81(1): 56-63. Article. 7,916  D1
2012 Alba-Domínguez, M.; López-Lera, A.; Garrido, S.; Nozal, P.; González-Granado, I.; Melero, J.; Soler-Palacín, P.; Cámara, C.; López-Trascasa, M. Complement factor I defi ciency: a not so rare immune defect. Characterization of new mutations and the fi rst large gene deletion. ORPHANET JOURNAL OF RARE DISEASES. 2012; 7: 42. Article.  4,315 Q1
2012 Marcos, C.; Lera, A. L.; Varela, S.; Linares, T.; Álvarez-Eire, M. G.; López-Trascasa, M. Clinical, biochemical, and genetic characterization of type III hereditary angioedema in 13 Northwest Spanish families. ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY. 2012; 109(3): 195-200. Article. 3,449 Q1
2012 de la Cruz, R. M.; López-Lera, A.; López-Trascasa, M. Analysis of SERPING1 expression on hereditary angioedema patients: quantitative analysis of full-length and exon 3 splicing variants. IMMUNOLOGY LETTERS. 2012; 141(2): 158-164. Article.  2,337 Q3
2012 Hijosa, M. M.; Melgar, A. A.; Urrutia, M. J. M.; Meseguer, C.G.; Monereo, E. J.; Torres, M. N. Living-donor transplantation after excision of unrecognized renal cancer diagnosed after transplant. PEDIATRIC NEPHROLOGY. 2012; 27(12): 2319-2321. Article.  2,939 D1
2012 de Diego, R. P.; Lera, A. L.; Cerdán, A. F. High frequency in the delay in primary tooth loss in X-linked chronic granulomatous disease. CLINICAL IMMUNOLOGY. 2012; 145(1): 59-60. Letter. 3,771 Q2
2011 Leban, N.; Aloui, S.; Touati, D.; Lakhdhar, R.; Skhiri, H.; Lefranc, G.; Achour, A.; Elmay, M.; LÓpez-Trascasa, M.; SÁnchez-Corral, P.; Chibani, J.; Khelil, A. H. Atypical hemolytic uremic syndrome in the Tunisian population. INTERNATIONAL UROLOGY AND NEPHROLOGY. 2011; 43(2): 559-564. Article. 1,471 Q3
2011 Abraira, V.; Álvarez-Cermeno, J. C.; Arroyo, R.; Camara, C.; Casanova, B.; Cubillo, S.; de Andrés, C.; Espejo, C.; Fernández, O.; Ferrer, J.; Figueredo, M. A.; García-Merino, A.; García-Sánchez, M. I.; García-Trujillo, J. A.; Gómez, M.; González-Oria, C.; Gosis, A.; Izquierdo, G.; Jiménez, J.; López-Trascasa, M.; Montalban, X.; Moreno, M. J.; Muñoz, D.; Núñez, V.; Muriel, A.; Navarro, J.; Olascoaga, J.; Oreja-Guevara, C.; Prada, A.; Ramil, E.; Ramo-Tello, C.; Rodríguez, C.; Rodríguez, E.; Rodríguez-Frías, F.; Rodríguez-Antigüedad, A.; Rodríguez-Molina, J. J.; Ruiz, E.; Saiz, A.; Sarasola, E.; Simo, M.; Yague, J.; Villar, L. M. Utility of oligoclonal IgG band detection for MS diagnosis in daily clinical practice. JOURNAL OF IMMUNOLOGICAL METHODS. 2011; 371(01 feb): 170-173. Article. 2,203 Q3
2011 Strobel, S.; Abarrategui-Garrido, C.; Fariza-Requejo, E.; Seeberger, H.; Sánchez-Corral, P.; Jozsi, M. Factor H-related protein 1 neutralizes anti-factor H autoantibodies in autoimmune hemolytic uremic syndrome. KIDNEY INTERNATIONAL. 2011; 80(4): 397-404. Article. 6,606 D1
2011 de la Cruz, R. M.; López-Lera, A.; López-Trascasa, M. Analysis of SERPING1 expression on hereditary angioedema patients: Quantitative analysis of full-length and exon 3 splicing variants. IMMUNOLOGY
LETTERS. 2011; 141(2): 158-164. Article.
2,526 Q3
2011 Caballero, T.; Baeza, M. L.; Cabañas, R.; Campos, A.; Cimbollek, S.; Gómez-Traseira, C.; González-Quevedo, T.; Guilarte, M.; Jurado-Palomo, J.; Larco, J. I.; López-Serrano, M. C.; López-Trascasa, M.; Marcos, C.; Muñoz-Caro, J. M.; Pedrosa, M.; Prior, N.; Rubio, M.; Sala-Cunill, A. Consensus Statement on the Diagnosis, Management, and Treatment of Angioedema Mediated by Bradykinin. Part II. Treatment, Follow-up, and Special Situations. JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY. 2011; 21(6): 422-441. Review. 2,269 Q3
2011 Caballero, T.; Baeza, M. L.; Cabañas, R.; Campos, A.; Cimbollek, S.; Gómez-Traseira, C.; González-Quevedo, T.; Guilarte, M.; Jurado-Palomo, J.; Larco, J. I.; López-Serrano, M. C.; López-Trascasa, M.; Marcos, C.; Muñoz-Caro, J. M.; Pedrosa, M.; Prior, N.; Rubio, M.; Sala-Cunill, A. Consensus Statement on the Diagnosis, Management, and Treatment of Angioedema Mediated by Bradykinin. Part I. Classification, Epidemiology, Pathophysiology, Genetics, Clinical Symptoms, and Diagnosis. JOURNAL OF INVESTIGATIONAL
ALLERGOLOGY AND CLINICAL IMMUNOLOGY. 2011; 21(5): 333-347. Review.
2,269 Q3
2011 Thelwell, C.; Rigsby, P.; Longstaff, C. (Lopez Trascasa, M.). An international collaborative study to establish the WHO 1st international standards for C1-inhibitor, plasma and concentrate. JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 2011; 9(10): 2097-299. Editorial Material. 5,731 Q1
2011 Lopez-Lera, A.; Garrido, S.; Roche, O.; López-Trascasa, M. SERPING1 mutations in 59 families with hereditary angioedema. MOLECULAR IMMUNOLOGY. 2011; 49(01 feb): 18-27. Article. 2,897 Q2
2010 Fuentes, G. M. C.; Meseguer, C. G.; Carrión, A. P.; Hijosa, M. M.; García-Pose, A.; Melgar, A. A.; Torres, M. N. Long-term outcome of focal segmental glomerulosclerosis after pediatric renal transplantation. PEDIATRIC NEPHROLOGY. 2010; 25(3): 529-534. Article. 2,183 Q2
2010 Barroso, S.; López-Trascasa, M.; Merino, D.; Álvarez, A. J.; Nuñez-Roldán, A; Sánchez, B. C7 Deficiency and Meningococcal Infection Susceptibility in Two Spanish Familias. SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2010; 72(1) 38-43. Article. 1,935
Q4
2010 Romanelli, V.; Belinchón, A; Benito-Sanz, S.; Martínez-Glez, V.; Gracia-Bouthelier, R.; Heath, K. E.; Campos-Barros, A.; García-Minaur, S.; Fernández, L.; Meneses, H.; López-Siguero, J. P.; Guillen-Navarro, E.; Gómez-Puertas, P.; Wesselink, J. J.; Mercado, G.; Esteban-Marfil, V.; Palomo, R.; Mena, R.; Sanchez, A.; del Campo, M.; Lapunzina, P. CDKN1C (p57(Kip2)) Analysis in Beckwith-Wiedemann Syndrome (BWS) Patients: Genotype-Phenotype Correlations, Novel Mutations, and Polymorphisms. AMERICAN JOURNAL OF MEDICAL GENETICS PART A. 2010; 152A (6): 1390-1397. Article. 2,505
Q2
2010 Fuentes, G. M. C.; Román, L. E.; Hijosa, M. M.; Torres, M. N. Acute renal failure due to bilateral pieloureteral stone impaction in a 10-month-old boy. CLINICAL AND EXPERIMENTAL NEPHROLOGY. 2010; 14(4): 401-403. Article. 1,46 Q3
2010 Álvarez-Twose, I.; de Olano, D. G.; Sánchez-Muñoz, L.; Matito, A.; Esteban-López, M. I.; Vega, A.; Mateo, M. B.; de Durana, M. D. A. D.; de la Hoz, B.; Gil, M. D. D.; Caballero, T.; Rosado, A.; Matas, I. S.; Teodosio, C.; Jara-Acevedo, M.; Mollejo, M.; García-Montero, A.; Orfao, A.; Escribano, L. Clinical, biological, and molecular characteristics of clonal mast cell disorders presenting with systemic mast cell activation symptoms. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2010; 125(6): 1269-1278. Article. 9,273 Q1
2010 Piñana, E.; Lei, S. H.; Merino, R.; Melgosa, M.; De La Vega, R.; Gonzáles-Obeso, E.; Ramírez, E.; Borobia, A.; Carcas, A. DRESS-syndrome on sulfasalazine and naproxen treatment for juvenile idiopathic arthritis and reactivation of human herpevirus 6 in an 11-year-old caucasian boy. JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS. 2010; 35(3): 365-370. Article. 1,649
Q3
2010 Martínez-Barricarte, R.; Heurich, M.; Valdés-Canedo, F.; Vázquez-Martul, E.; Torreira, E.; Montes, T.; Tortajada, A.; Pinto, S.; López-Trascasa, M.; Morgan, B. P.; Llorca, O.; Harris, C. L.; de Cordoba, S. R. Human C3 mutation reveals a mechanism of dense deposit disease pathogenesis and provides insights into complement activation and regulation. JOURNAL OF CLINICAL INVESTIGATION. 2010; 120(10): 3702-3712. Article. 14,152
Q1
2010 Jurado-Palomo, J.; Cabanas, R.; Prior, N.; Bobolea, I. D.; Fiandor-Román, A. M.; López-Serrano, M. C.; Quirce, S.; Bellón, T. Use of the Lymphocyte Transformation Test in the Diagnosis of DRESS Syndrome Induced by Ceftriaxone and Piperacillin-tazobactam: Two Case Reports. JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY. 2010; 20(5): 433-436. Article. 1,489
Q3
2010 Sánchez-Corral, P.; Melgosa, M. Advances in understanding the aetiology of atypical Haemolytic Uraemic Síndrome. BRITISH JOURNAL OF HAEMATOLOGY. 2010; 150(5): 529-542. Review. 4,942 Q1
2010 López-Lera, A.; Favier, B.; de la Cruz, R. M.; Garrido, S.; Drouet, C.; López-Trascasa, M. A new case of homozygous C1-inhibitor deficiency suggests a role for Arg378 in the control of kinin pathway activation. JOURNAL OF ALLERGY AND CLINICAL. 2010; 126(6): 1307-1310. Letter. 9,273
Q1
2009 Cruzado, JM; de Cordoba, SR; Melilli, E; Bestard, O; Rama, I; Sanchez-Corral, P; Lopez-Trascasa, M; Navarro, I; Torras, J; Goma, M; Grinyo, JM. Successful Renal Transplantation in a Patient with Atypical Hemolytic Uremic Syndrome Carrying Mutations in Both Factor I and MCP. AMERICAN JOURNAL OF TRANSPLANTATION. 2009; 9(6): 1477-1483 6,433
Q1
2009 Vaudry, W; Ettenger, R; Jara, P; Varela-Fascinetto, G; Bouw, MR; Ives, J; Walker, R. Valganciclovir Dosing According to Body Surface Area and Renal Function in Pediatric Solid Organ Transplant Recipients. AMERICAN JOURNAL OF TRANSPLANTATION. 2009; 9(3): 636-643 6,433
Q1
2009 Rubio Rodríquez F., Melgosa Hijosa M. Hipertensión arterial en la infancia. ANALES DE PEDIATRIA CONTINUADA. 2009; 7: 270-278 N/A
N/A
2009 Pedrosa, M; Caballero, T; Gomez-Traseira, C; Olveira, A; Lopez-Serrano, C. Usefulness of abdominal ultrasonography in the follow-up of patients with hereditary C1-inhibitor deficiency. ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY. 2009; 102(6): 483-486 2,457
Q2
2009 Jurado-Palomo, J; Caballero, T; Fernandez-Nieto, M; Quirce, S. OCCUPATIONAL ASTHMA CAUSED BY ARTIFICIAL CYANOACRYLATE FINGERNAILS. ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY. 2009; 102(5): 440-441 2,457
Q2
2009 Valdivieso, R; Cevallos, F; Caballero, MT; Quirce, S. Chronic urticaria caused by folic acid. ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY. 2009; 103(1): 81-82 2,457
Q2
2009 Abarrategui-Garrido, C; Martinez-Barricarte, R; Lopez-Trascasa, M; de Cordoba, SR; Sanchez-Corral, P. Characterization of complement factor H-related (CFHR) proteins in plasma reveals novel genetic variations of CFHR1 associated with atypical hemolytic uremic syndrome. BLOOD. 2009; 114(19): 4261-4271 10,555
Q1
2009 Garcia, BE; Gamboa, PM; Asturias, JA; Lopez-Hoyos, M; Sanz, ML. Guidelines on the Clinical Usefulness of Determination of Specific Immunoglobulin E to Foods. JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY. 2009; 19(6): 423-432 1,189
Q3
2009 Saland, JM; Ruggenenti, P; Remuzzi, G. Liver-Kidney Transplantation to Cure Atypical Hemolytic Uremic Syndrome. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 2009; 20(5): 940-949 7,689
Q1
2009 Lopez-Trascasa, M; Gil-Aguado, A; Capozzi, A; Sorice, M. Association of anti-C1 inhibitor and anti-protein S antibodies in a patient with primary antiphospholipid syndrome. LUPUS. 2009; 18(2): 182-183 2,586
Q3
2009 Lopez-Lera, A; Garrido, S; de la Cruz, RM; Fontan, G; Lopez-Trascasa, M. Molecular characterization of three new mutations causing C5 deficiency in two non-related families. MOLECULAR IMMUNOLOGY. 2009; 46: 2340-2347 3,202
Q3