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Composition
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Name
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Position
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Institution
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Talía Sainz Costa
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Facultativo Especialista de Área en Pediatría
Profesora Asociada
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Hospital Universitario La Paz
Universidad Autónoma Madrid
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Jorge Atucha Margolles
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Técnico de Laboratorio
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FIBHULP
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Fernando Baquero Artigao
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Facultativo Especialista de Área de Pediatría
Profesor Colboarador
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Hospital Universitario La Paz
Universidad Complutense de Madrid
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Blanco Bravo Queipo de Llano
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Facultativo Especialista de Área de Pediatría
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Hospital Universitario La Paz
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Jorge Bustamante Amador
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Investigador Predoctoral
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Hospital Universitario La Paz
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Francisco José Climent Alcalá
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Facultativo Especialista de Área de Pediatría. Unidad de Patología Compleja
Colaborador docente
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Hospital Universitario La Paz
Univesidad Autónoma de Madrid
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Lucía Escolano Taravillo
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Investigador Predoctoral
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Hospital Universitario La Paz
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Luis Escosa García
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Facultativo Especialista de Área en Pediatría
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Hospital Universitario La Paz
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Jaime Delgado Pérez
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Investigador Predoctoral
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Hospital Universitario La Paz
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Miguel García Boyano
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Investigador Predoctoral
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Hospital Universitario La Paz
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Marta García Fernández de Villalta
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Facultativo Especialista de Área de Pediatría
Colaborador Clínico Docente
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Hospital Universitario La Paz
Univesidad Autónoma de Madrid
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María Milagros García López de Hortelano
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Médico Adjunto de Pediatría Hospitalaria y Enfermedades Infecciosas y Tropicales
Colaborador Clínico Docente
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Hospital Universitario La Paz
Universidad Autónoma de Madrid
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Isabel Mellado Sola
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Médico Interno Residente
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Hospital Universitario La Paz
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María Pérez Pascual
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Médica Adjunta en Pediatría
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Hospital Universitario La Paz
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Roi Piñeiro Pérez
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Jefe Asociado del Servicio de Pediatría
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Hospital General de Villalba
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Paula Rodríguez Molino
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Contrato Rio Hortega
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Hospital Universitario La Paz
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Strategic Objective
1. Vertically acquired HIV infection in children: Comorbidities, biomarkers, HIV reservoir, new therapeutic approaches.
2. Epidemiology of Paediatric Tuberculosis is Spain: molecular epidemiology of drug resistant strains, new diagnostic tools and new drugs for TB: Pharmacodynamics in children and TB-drugs Off-label use in paediatrics.
3. Congenital infections: burden of disease, prompt diagnosis and in-utero and postnatal management, host immune response.
4. Epidemiology of imported and emergent diseases in children: Identification and management of emergent outbreaks. Immuno-pathogenesis, preventive measures and management.
5. Immunization strategies in children: immune response in high risk patient’s vaccine effectiveness and barriers.
Research Lines
• Vertically acquired HIV infection in children
- Immuno-pathogenesis: Immune-activation, inflammation and biomarkers
- Epidemiology, immuno-virological factors
- Comorbidities, long term follow-up, cardiovascular risk, bone disorders, metabolic abnormalities, neurocognitive impairment, renal dysfunction.
- Antiretroviral treatment: new drugs, resistances, dosage, toxicity in children, simplification strategies.
- HIV eradication: barriers, HIV reservoir, new antiretroviral drugs and other strategies to achieve HIV replication control.
- Gut Microbiota and bacterial traslocation intestinal as modulating factors for inflammation and immune-activation in HIV-infected children.
- Transition to adult care: barriers, strategies to maintain adherence to care.
• Epidemiology of paediatric Tuberculosis (TB).
- Epidemiology of paediatric TB. Paediatric cases as as a sentinel for burden of diseases.
- Molecular epidemiology of paediatric TB: resistant strains.
- Immuno-pathogenesis: New diagnostic tools in special Populations: HIV-infected, ID patients, migrants and Internationally adopted children
- Management of critical situations. Neonatal TB, multidrug resistant and extra-pulmonary TB.
- New fixed-dosed combinations. Off label drugs in children. Pharmacodinamic and pharmacokinetic.
• Congenital infectious diseases
- Congenital Citomegalovirus and Toxoplasma infections: diagnostic barriers, prognostic factors, new therapeutic approaches.
- CHAGAS disease and congenital TB: diagnostic barriers, prognostic factors, pharmacokinetics in newborns and new drugs.
• Epidemiology of imported and emergent diseases in children
- Paediatric International Outbreaks: Epidemiology and public health impact: Zika. Rabies. Dengue. Chikungunya. Haemorragic fevers, Mers-co.
- Imported diseases in Spain: epidemiology and special populations: adopted, migrant, refugees, travelers and ID children
• Immunization strategies in children, including high risk patients
- Immunization and vaccine response in special populations: immunocompromised children, transplant recipients, chronic patients, HIV-infected, migrants.
- Vaccine immunogenicity: barriers in paediatric populations.
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